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Hnf1btm1Ics
Targeted Allele Detail
Summary
Symbol: Hnf1btm1Ics
Name: HNF1 homeobox B; targeted mutation 1, Mouse Clinical Institute
MGI ID: MGI:5471835
Gene: Hnf1b  Location: Chr11:83741035-83796743 bp, + strand  Genetic Position: Chr11, 51.23 cM
Alliance: Hnf1btm1Ics page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:194051
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    LoxP sites were inserted flanking exon 4 via homologous recombination. (J:194051)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hnf1b Mutation:  16 strains or lines available
References
Original:  J:194051 Heliot C, et al., HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85
All:  5 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory